Abrindo uma janela para a mente
NOVA GALERIA DE IMAGENS
http://www.estimulacao.com.br/galeria.htm
quinta-feira, 24 de setembro de 2009
IMAGEM Estimulação Magnética Transcraniana EMTr - uma janela para a mente IMAGE rTMS
NOVA GALERIA DE IMAGENS
OU
quarta-feira, 23 de setembro de 2009
Funçoes do Cérebro Esquerdo e Direito
CEREBRO ESQUERDO E DIREITO FUNCOES
FUNCOES DO CEREBRO ESQUERDO | FUNCOES DO CEREBRO DIREITO |
usa a lógica | usa sentimento |
Orientado por detalhes | Orientado por grandes figuras |
Regido por fatos | Regido por imaginação |
palavras e linguagem | símbolos e imagens |
presente e passado | presente e futuro |
matemática e ciência | Filosofia e Religião |
pode compreender | pode "intuir" (ou seja, sentido) |
saber | acredita |
reconhece | aprecia |
percepção do padrão /ordem | percepção espacial |
sabe o nome do objeto | conhece a função de objeto |
baseado em realidade | Baseado em fantasia |
estratégias de formas | apresenta possibilidades |
prático | impetuoso |
seguro | assume riscos |
A estimulação magnética transcraniana EMT pode agir seletivamente sobre os hemisférios cerebrais
domingo, 13 de setembro de 2009
GALERIA DE IMAGENS ESTIMULACAO MAGNETICA CBREMT
"Galeria de Imagens do CBREMT"
"Acesse o site http://drbroder.sites.uol.com.br/ para ver a galeria de imagens
quinta-feira, 10 de setembro de 2009
OTIMIZAÇÃO DO POSICIONAMENTO DA BOBINA DE EMTR NA DEPRESSAO
OTIMIZAÇÃO DO POSICIONAMENTO DA BOBINA DE EMTR NA DEPRESSAO
Biol Psychiatry. 2009 Sep 1;66(5):509-15. Epub 2009 Jul 9.Biol Psychiatry. 2009 Sep 1;66(5):509-15. Epub 2009 Jul 9.
Localização da bobina pre-frontal mais lateral e anterior é associada a melhor resposta antidepressiva da estimulacao magnetica transcraniana
RTMS: OPTIMIZED COIL POSITIONING IN DEPRESSION
Biol Psychiatry. 2009 Sep 1;66(5):509-15. Epub 2009 Jul 9.Biol Psychiatry. 2009 Sep 1;66(5):509-15. Epub 2009 Jul 9.
More lateral and anterior prefrontal coil location is associated with better repetitive transcranial magnetic stimulation antidepressant response.
Herbsman T, Avery D, Ramsey D, Holtzheimer P, Wadjik C, Hardaway F, Haynor D, George MS, Nahas Z.
Department of Psychiatry, Brain Stimulation Laboratory, Center for Advanced Imaging Research, Medical University of South Carolina, Charleston, South Carolina 29425, USA.
BACKGROUND: The left dorsolateral prefrontal cortex (DLPFC) is the most commonly used target for transcranial magnetic stimulation (TMS) in the treatment of depression. The “5-cm rule” is an empiric method used for probabilistic targeting of the DLPFC in most clinical trials. This rule may be suboptimal, as it does not account for differences in skull size or variations in prefrontal anatomy relative to motor cortex location. This study is a post hoc analysis of data from a large repetitive TMS (rTMS) trial in which we examined the variability of coil placement and how it affects antidepressant efficacy. METHODS: Fifty-four depressed subjects enrolled in a randomized, single-site trial received either active rTMS or sham for 3 weeks. Prior to treatment initiation, investigators placed vitamin E capsules at the point of stimulation and used a high-resolution magnetic resonance imaging (MRI) scan to image these fiducials relative to anatomy. We employed a semi automated imaging-processing algorithm to localize the cortical region stimulated. RESULTS: Active TMS significantly reduced Hamilton Depression Rating Scale (HDRS) scores. A linear model for this improvement involving the coordinates of the stimulated cortex location, age, and treatment condition was highly significant. Specifically, individuals with more anterior and lateral stimulation sites were more likely to respond. CONCLUSIONS: These results suggest that within the general anatomical area targeted by the 5-cm rule, placing the TMS coil more laterally and anteriorly is associated with improved response rates in TMS depression studies. Controlled studies testing this anatomical hypothesis are needed.
PMID: 19545855 [PubMed - in process]
Biol Psychiatry. 2009 Sep 1;66(5):509-15. Epub 2009 Jul 9.Biol Psychiatry. 2009 Sep 1;66(5):509-15. Epub 2009 Jul 9.
Localização da bobina pre-frontal mais lateral e anterior é associada a melhor resposta antidepressiva da estimulacao magnetica transcraniana
RTMS: OPTIMIZED COIL POSITIONING IN DEPRESSION
Biol Psychiatry. 2009 Sep 1;66(5):509-15. Epub 2009 Jul 9.Biol Psychiatry. 2009 Sep 1;66(5):509-15. Epub 2009 Jul 9.
More lateral and anterior prefrontal coil location is associated with better repetitive transcranial magnetic stimulation antidepressant response.
Herbsman T, Avery D, Ramsey D, Holtzheimer P, Wadjik C, Hardaway F, Haynor D, George MS, Nahas Z.
Department of Psychiatry, Brain Stimulation Laboratory, Center for Advanced Imaging Research, Medical University of South Carolina, Charleston, South Carolina 29425, USA.
BACKGROUND: The left dorsolateral prefrontal cortex (DLPFC) is the most commonly used target for transcranial magnetic stimulation (TMS) in the treatment of depression. The “5-cm rule” is an empiric method used for probabilistic targeting of the DLPFC in most clinical trials. This rule may be suboptimal, as it does not account for differences in skull size or variations in prefrontal anatomy relative to motor cortex location. This study is a post hoc analysis of data from a large repetitive TMS (rTMS) trial in which we examined the variability of coil placement and how it affects antidepressant efficacy. METHODS: Fifty-four depressed subjects enrolled in a randomized, single-site trial received either active rTMS or sham for 3 weeks. Prior to treatment initiation, investigators placed vitamin E capsules at the point of stimulation and used a high-resolution magnetic resonance imaging (MRI) scan to image these fiducials relative to anatomy. We employed a semi automated imaging-processing algorithm to localize the cortical region stimulated. RESULTS: Active TMS significantly reduced Hamilton Depression Rating Scale (HDRS) scores. A linear model for this improvement involving the coordinates of the stimulated cortex location, age, and treatment condition was highly significant. Specifically, individuals with more anterior and lateral stimulation sites were more likely to respond. CONCLUSIONS: These results suggest that within the general anatomical area targeted by the 5-cm rule, placing the TMS coil more laterally and anteriorly is associated with improved response rates in TMS depression studies. Controlled studies testing this anatomical hypothesis are needed.
PMID: 19545855 [PubMed - in process]
Eficacia da Estimulacao Magnetica Transcraniana na Mania
Efficacy of high frequency (rapid) suprathreshold repetitive transcranial magnetic stimulation of right prefrontal cortex in bipolar mania: A randomized sham controlled study
Volume 117, Issue 3, Pages 146-150 (October 2009)
Samir Kumar Praharaja, Daya Rama, Manu Arorab
Received 26 September 2008; received in revised form 30 December 2008; accepted 31 December 2008.
Abstract
Objective
To examine the efficacy of adjunctive right prefrontal high-frequency suprathreshold rTMS treatment in bipolar affective disorder, mania patients as compared to sham stimulation.
Method
41 right handed bipolar mania patients were randomized to receive daily sessions of active or sham rTMS (20 Hz, 110% of MT, 20 trains, 10 s intertrain interval) over the right dorsolateral prefrontal cortex for 10 days. Mania was rated using Young Mania Rating Scale (YMRS) and Clinical Global Impression (CGI) at baseline, and after 5th and 10th rTMS.
Result
For YMRS scores, repeated measures ANOVA showed a significant effect of treatment over time as shown by interaction effect (F = 12.95, df = 1.51/58.94, p < 0.001, Greenhouse-Geisser corrected). For CGI-S, repeated measures ANOVA showed a significant interaction effect of treatment over time (F = 5.34, df = 1.36/53.01, p = 0.016, Greenhouse-Geisser corrected).
Conclusion
High-frequency supra-threshold right prefrontal rTMS in bipolar, mania patients was well tolerated and found to be effective as add-on to standard pharmacotherapy.
Keywords: Bipolar affective disorder, Mania, rTMS
Volume 117, Issue 3, Pages 146-150 (October 2009)
Samir Kumar Praharaja, Daya Rama, Manu Arorab
Received 26 September 2008; received in revised form 30 December 2008; accepted 31 December 2008.
Abstract
Objective
To examine the efficacy of adjunctive right prefrontal high-frequency suprathreshold rTMS treatment in bipolar affective disorder, mania patients as compared to sham stimulation.
Method
41 right handed bipolar mania patients were randomized to receive daily sessions of active or sham rTMS (20 Hz, 110% of MT, 20 trains, 10 s intertrain interval) over the right dorsolateral prefrontal cortex for 10 days. Mania was rated using Young Mania Rating Scale (YMRS) and Clinical Global Impression (CGI) at baseline, and after 5th and 10th rTMS.
Result
For YMRS scores, repeated measures ANOVA showed a significant effect of treatment over time as shown by interaction effect (F = 12.95, df = 1.51/58.94, p < 0.001, Greenhouse-Geisser corrected). For CGI-S, repeated measures ANOVA showed a significant interaction effect of treatment over time (F = 5.34, df = 1.36/53.01, p = 0.016, Greenhouse-Geisser corrected).
Conclusion
High-frequency supra-threshold right prefrontal rTMS in bipolar, mania patients was well tolerated and found to be effective as add-on to standard pharmacotherapy.
Keywords: Bipolar affective disorder, Mania, rTMS
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